CRISPR preprints

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Theme editors: Chunjie Liu


Preprint Authors Date Reviews & Comments Intersect Actions
Genetic and physiological mechanisms of freezing tolerance in locally adapted populations of a winter annual 18th May 2019
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Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption 18th May 2019
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Ordered insertional mutagenesis at a single genomic site enables lineage tracing and analog recording in mammalian cells 17th May 2019
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Gene knock-ins in Drosophila using homology-independent insertion of universal donor plasmids 17th May 2019
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Advancing functional genetics through Agrobacterium-mediated insertional mutagenesis and CRISPR/Cas9 in the commensal and pathogenic yeast Malassezia furfur 16th May 2019
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Proxies of CRISPR-Cas9 activity to aid in the identification of mutagenized Arabidopsis plants 16th May 2019
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SpCas9 activity prediction by DeepCas9, a deep learning-based model with unparalleled generalization performance 16th May 2019
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Compromised function of an ESCRT complex promotes endolysosomal escape of tau seeds and propagation of tau aggregation 15th May 2019
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Genetic screening for single-cell variability modulators driving therapy resistance 15th May 2019
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The Salt-Inducible Kinase inhibitor YKL-05-099 suppresses MEF2C function and acute myeloid leukemia progression in vivo 15th May 2019
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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy 15th May 2019
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A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila 14th May 2019
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Dissecting the functions of NIPBL using genome editing: The importance of the N-terminus of NIPBL in transcriptional regulation 12th May 2019
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Efficient strategies to detect genome editing and integrity in CRISPR-Cas9 engineered ESCs 12th May 2019
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In silico experiments validate that twenty nucleotide spacer sequence provides precise targeting of bacterial genes in CRISPR-Cas9 12th May 2019
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Mutational mimics of allosteric effectors: a genome editing design to validate allosteric drug targets 11th May 2019
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Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell Carcinoma 10th May 2019
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CRISPR interference at the FAAH-OUT genomic region reduces FAAH expression 10th May 2019
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CRISPR adenine and cytosine base editors with reduced RNA off-target activities 10th May 2019
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Tissue-specific Genome Editing in vivo by MicroRNA-repressible Anti-CRISPR Proteins 9th May 2019
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